Stem cell transplantation as treatment for children with autism

Stem cell transplantations are performed to treat certain forms of cancer but also to treat some other rarer disorders. Today stem cell clinics advertise stem cell transplantation as a treatment to disorders like autism at high costs. There are however doubts about the efficacy and safety of these treatments.

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SBU Enquiry Service

Responds to queries received from Swedish healthcare and social service providers, or governmental organisations. Queries have a limited scope and the process is designed to enable a more rapid response, typically within two to three months. Reports are based on systematic reviews, that are identified through structured searches and critically appraised for risk of bias.

Published: Report no: ut201827

Question

Which scientific studies have investigated stem cell transplantation as treatment for children with autism?

Identified literature

  1. Chez M, Lepage C, Parise C, Dang-Chu A, Hankins A, Carroll M. Safety and Observations from a Placebo-Controlled, Crossover Study to Assess Use of Autologous Umbilical Cord Blood Stem Cells to Improve Symptoms in Children with Autism. Stem Cells Translational Medicine 2018;7:333-341.
  2. Lv YT, Zhang Y, Liu M, Qiuwaxi JN, Ashwood P, Cho SC, et al. Transplantation of human cord blood mononuclear cells and umbilical cord-derived mesenchymal stem cells in autism. J Transl Med 2013;11:196.
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